Associate Scientist In Vivo Pharmacology Gene Therapy in Indianapolis

Job Description

Join American pharmaceutical leader Eli Lilly and Company, currently hiring Associate Scientist In Vivo Pharmacology Gene Therapy in Indianapolis, Apply Lilly careers in Indianapolis Indiana.


Position : Associate Scientist In Vivo Pharmacology Gene Therapy

Location : Indianapolis, Indiana

Job id: R-33486


Job Details

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.Organization Overview:
At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.Associate Scientist, In Vivo Pharmacology Gene Therapy (P1-P4)About Prevail TherapeuticsPrevail, a wholly owned subsidiary of Eli Lilly and Company, is a biotechnology company focused on developing novel gene therapies for Parkinson’s disease and other genetically defined neurodegenerative diseases. While being based in the Alexandria Centre for life Sciences on the East Side of Manhattan in New York city, Prevail has recently branched out to Indianapolis where the In-vivo pharmacology team will be present.Position SummaryThe Associate Scientist, In Vivo Pharmacology, will participate and contribute to the in-vivo pharmacology lab, located in Indianapolis, to support the discovery and optimization of novel therapeutic candidates for Gene Therapy. As part of the Prevail discovery team, s/he will be a key driver to advance novel targets for neurodegenerative disorders, as well as exploring AAV biodistribution and clearance.Responsibilities Conduct in vivo pharmacology experiments and studies to characterize activity of gene therapy vectors in mouse modelsAssist in conducting in-vivo studies to support the in vitro team of Prevail in NYAssist in the development and characterization of novel in-vivo modelsCollaborate with cross-functional partners (Preclinical, toxicology, PK/PD modelling) to ensure the translation from discovery to developmentPerform studies to investigate the in vivo distribution and clearance of AAVBasic QualificationsBS and/or MS in biology or related disciplines with experience (Academic or Industry) in Gene therapy or Neuroscience is required.
 Additional Skills/PreferencesExpert in vivo skills including rodent handling, dosing (iv, ip, po, etc) and harvesting tissues/fluidsCandidates with experience doing stereotaxic surgery are preferredPrior experience in macromolecule distribution and metabolismExperience with ex-vivo assays is a plus such as ELISAs, WB, qPCR and histology techniquesExperience in flow-cytometry is desiredPassion, knowledge and experience in neuroscience or rare disease researchStrong analytic thinking skills. Demonstrated ability to articulate issues, and extract and synthesize complex issues into key focus.Creative and curious. Can quickly adapt in a fast-paced working environmentStrong inter-personal and communication skills. Proven record to collaborate and network across a wide variety of functions and work effectively with internal and external partners.Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).



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